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Expert Consulting and ‘Omics Services
At Spectrus, we take pride in being a flexible, accountable, and resourceful CRO provider for our clients’ mass spectrometry needs. Explore our solutions, instrumentation, and technology below.
Consulting Services and Method Design
Our clients have direct access to experience and insight from highly specialized experts in proteomics and mass spectrometry. Upfront consultation is invaluable for determining whether mass spec can provide useful answers, what method will generate relevant data, and how to structure the project effectively. Ongoing communication throughout each project ensures a successful outcome.
Quality and Expertise Are Essential: Having method design and sample processing done properly the first time saves money and keeps projects on track.
Cutting-Edge Sample-Processing Technology
We perform sample processing in-house using sensitive chromatography and high-resolution mass spectrometry instrumentation. Our clients rely on us for utmost precision and quality control in handling their samples. We run an efficient lab to provide a timely turnaround on samples.
Rigorous Data Analysis and Actionable Insights
Our data transformation and statistical analyses tools ensure the results provided are accurate and meaningful. Our lead scientists bring an experienced eye to interpreting data and presenting the findings in a clear, useable way. Spectrus’ clients have certainty in the quality and relevance of their data and appreciate the ability to verify and validate findings from other data sources.
Data Analysis Technology
Mass Spectrometry and ‘Omics Services
Spectrus specializes in proteomics, protein & peptide discovery and quantitation, post translational modifications, and metabolomics.
Quantitative Proteomics
- Tandem Mass Tag Labeling
- Targeted Proteomics by Multiple-Reaction Monitoring (MRM) or Parallel-Reaction Monitoring (PRM)
- Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC)
- Label-Free Quantitation
- Cystine Target Profiling
Post Translational Modification Analysis
- Analysis of Post-Translational Modifications
- Analysis of Glycopeptides and Determination of the Site Glycosylation
- Glycosylation Profiling
- Phosphorylation Site Identification and Quantitation
Protein Identification
- In-gel digestion and LCMS
- Protein Profiling
- Peptide Mapping
- Protein Target Identification
- Intact Mass Analysis
- De novo Protein Sequencing
Other ‘Omics (Metabolomics & Lipidomics)
- Phosphoproteomics
- Glycomics
- Metabolomics
- Lipidomics
- Epigenetics
Additional Services
- Western Blot and Cell Culture
- Pharmacokinetics
We Can Help with Special Projects
Loading Ratios
Antibody-drug Conjugate Loading Ratios
Tethered Ligands
Selection/Enrichment Using Tethered Ligands
Quality Control
Quality Control of Therapeutic Protein Production Lots
Studies
Peptide Cellular Uptakes Studies Using Labeled or Unlabeled Substrates
Characterization
Biotherapeutics Characterization
2D Chromatography
Small Molecule or Peptide Screening Using 2D Chromatography
Accelerate New Technology Development
Engage us to test and qualify your new diagnostic or therapeutic device. We have experience developing proof-of-concepts in the areas of plate-based diagnostics, immune cell activation. and bioanalytical devices.
Meet Data Requirements for Filing
As new requirements continue to emerge for FDA filings, we help our clients gather and present the appropriate mass spectrometry data to support their research.
Tell Us Your Project Requirements
We are a flexible partner and will work with you to find the right approach to meet your project needs in alignment with your budget. Schedule a complimentary consultation with our lead scientists.