What We Offer

Expert Consulting and ‘Omics Services

At Spectrus, we take pride in being a flexible, accountable, and resourceful CRO provider for our clients’ mass spectrometry needs. Explore our solutions, instrumentation, and technology below.

Consulting Services and Method Design

Our clients have direct access to experience and insight from highly specialized experts in proteomics and mass spectrometry. Upfront consultation is invaluable for determining whether mass spec can provide useful answers, what method will generate relevant data, and how to structure the project effectively. Ongoing communication throughout each project ensures a successful outcome.

Quality and Expertise Are Essential: Having method design and sample processing done properly the first time saves money and keeps projects on track.

Cutting-Edge Sample-Processing Technology

We perform sample processing in-house using sensitive chromatography and high-resolution mass spectrometry instrumentation. Our clients rely on us for utmost precision and quality control in handling their samples. We run an efficient lab to provide a timely turnaround on samples.

lab equipment
lab equipment

Rigorous Data Analysis and Actionable Insights

Our data transformation and statistical analyses tools ensure the results provided are accurate and meaningful. Our lead scientists bring an experienced eye to interpreting data and presenting the findings in a clear, useable way. Spectrus’ clients have certainty in the quality and relevance of their data and appreciate the ability to verify and validate findings from other data sources.

Data Analysis Technology

Mass Spectrometry and ‘Omics Services

Spectrus specializes in proteomics, protein & peptide discovery and quantitation, post translational modifications, and metabolomics.

Quantitative Proteomics

  • Reporter Ion Labeling
  • Targeted Proteomics and LCMS
  • Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC)
  • Label-Free Quantitation
  • Cystine Target Profiling

Post Translational Modification Analysis

  • Analysis of Post-Translational Modifications
  • Analysis of Glycopeptides and Determination of the Site Glycosylation
  • Glycosylation Profiling
  • Phosphorylation Site Identification and Quantitation

Protein Identification

  • In-gel digestion and LCMS
  • Protein Profiling
  • Peptide Mapping
  • Protein Target Identification
  • Intact Mass Analysis
  • De novo Protein Sequencing

Other ‘Omics (Metabolomics & Lipidomics)

  • Phosphoproteomics
  • Glycomics
  • Metabolomics
  • Lipidomics
  • Epigenetics

Additional Services

  • Western Blot and Cell Culture
  • Pharmacokinetics
  • Amino Acid Development

We Can Help with Special Projects

Loading Ratios

Antibody-drug Conjugate Loading Ratios

Tethered Ligands

Selection/Enrichment Using Tethered Ligands

Quality Control

Quality Control of Therapeutic Protein Production Lots

Studies

Peptide Cellular Uptakes Studies Using Labeled or Unlabeled Substrates

Characterization

Biotherapeutics Characterization

2D Chromatography

Small Molecule or Peptide Screening Using 2D Chromatography

Accelerate New Technology Development

Engage us to test and qualify your new diagnostic or therapeutic device.  We have experience developing proof-of-concepts in the areas of plate-based diagnostics, immune cell activation. and bioanalytical devices.

Meet Data Requirements for Filing

As new requirements continue to emerge for FDA filings, we help our clients gather and present the appropriate mass spectrometry data to support their research.

Tell Us Your Project Requirements

We are a flexible partner and will work with you to find the right approach to meet your project needs in alignment with your budget. Schedule a complimentary consultation with our lead scientists.